Normal Human Chondrocytes are used for
experimental applications in joint research,
physiology, cellular function and differentiation.
Cryopreserved 19-CHON are shipped in second
passage. Proliferating 19-CHON are shipped in third
passage in T-flasks.
Chondrocytes are specialized cells which
produce and maintain the extracellular matrix of
cartilage and are the only cellular component of
cartilage. Although cartilage is not confined to
articulating joints, articular cartilage, especially
weight bearing joints, is an area of intense
because arthritis, joint injuries and joint
abnormalities cause wide spread disability.
GENTAUR Chondrocyte Cell are convenient
and easy to use, allowing the researcher to focus on
Chondrocytes are differentiated cells when isolated.
They lose their differentiated phenotype after
expansion in monolayer culture. By the second or
third passage the cells are almost completely
Chondrocytes can be expanded in
culture and then induced to re-differentiate.
In addition ChondroMaxTM is designed to
cultures for experimental applications including
studies on the formation, breakdown, and
regeneration of hyaline cartilage, Osteoarthritis
research and the proliferation and differentiation
GENTAUR cells, medium and reagents are quality
tested together and guaranteed to give optimum
performance as a complete "cell system".
Cells are tested for the presence of Collagen Type
at primary and/or after re-differentiation. Cells
tested for sulfated proteoglycans with Alcian Blue
stain after re-differentiation. Please note, the
differentiation system does not attempt to
the cells to hypertrophic state. The cells
are re-differentiated to produce Collagen Type II
do not necessarily produce Collagen Type X upon
All cells are performance assayed and test negative
for HIV-1, mycoplasma, Hepatitis-B, Hepatitis-C,
bacteria, yeast and fungi. Cell viability,
and proliferative capacity are measured after
recovery from cryopreservation. GENTAUR media
are optimized to grow specific types of normal
human cells. Each lot of medium is tested for the
support of cell viability and proliferative
Certificates of Analysis (CoA) for each cell strain
shipped with each order. CoA for all other products
are available upon request.