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Interferon alfa-2b (IFN a-2b)

 

 

l        Description

Recombinant Human Interferon alfa-2b is a sterile protein product for injection. rHuIFN a-2b is produced by recombinant DNA technology by Yeast carrying a genetically engineered plasmid containing human interferon alfa-2b gene. It is a highly purified protein containing 165 amino acids, and has a molecular weight of approximately19.3kD.

 

l        Indication

1.      Treatment of viral diseases including acute and chronic hepatitis, herpes zoster, condylomata acuminate

2.      Treatment of hairy cell leukemia

3.      Treatment of malignant melanoma

4.      Treatment of follicular lymphoma 

5.      Treatment of condylomata acuminate

6.      Indicated for AIDS-Related Kaposi’s Sarcoma

 

l        Pharmaceutical particulars

Sterile, clear, colorless and preservative-free liquid for injection in vials.

Dosage: 3 million IU (0.3ml)/vial

Reference: Current European Pharmacopoeia and Internal Requirement

Specific activity: ≥2.0×108 IU/mg

Purity (HPLC, SDS-PAGE): ≥98%

 

l        Composition

Active ingredient: Recombinant Human Interferon alfa-2b (rHuIFN a-2b)

Inactive ingredients: Sodium chloride, Polysobate-80, Dibasic Sodium Phosphate and Monobasic Sodium Phosphate.

 

l        Shelf life and storage conditions

 

 Finished formulation  Store at 2-8 for 2 years
 API (Concentrated solution)  Store at -70 for 12 months
 

 

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Last modified: 05/19/16