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Human active Tau Protein,  100 µg

Call for information.

 Alzheimer Mouse control slices

Hock C, Konietzko U, Streffer JR, Tracy J, Signorelli A, Muller-Tillmanns B,
Lemke U, Henke K, Moritz E, Garcia E, Wollmer MA, Umbricht D,
de Quervain DJF, Hofmann M, Maddalena A, Papassotiropoulos, Nitsch RM.
"Antibodies against -amyloid slow cognitive decline in Alzheimer's Disease".
Neuron 2003 (May 22) 38: 547 - 554.

een comment van de AD web-site (http://www.alzforum.org) :

"To measure the antibody response, Hock et al. used an assay they had developed earlier,
which measures the patients serum antibodies directed against -amyloid in brain slices
of APP-transgenic mice.
Called tissue amyloid plaque immunoreactivity (TAPIR),
this assay correlated better with clinical benefit than did more customary ELISA tests
measuring the binding of antibodies against synthetic A. Those with the highest TAPIR
scores also enjoyed the greatest protection from disease progression.
This could mean that functional improvement depends on conformation-specific antibodies
that TAPIR is better suited to picking up than ELISA, the authors suggest.

 

Sections through transgenic Alzheimer mouse brain for histology and immunohistochemistry, unstained

Sections through transgenic Alzheimer mouse brain for histology and immunohistochemistry, unstained
(Reference #GEN-3701)

vial with 2 brain sections floating, fixed, unstained

Brains of transgenic Alzheimer mice, aged 1.5 - 3 years and bearing numerous amyloid plaques in subiculum, cortex and hippocampus were fixed in 4% paraformaldehyde. 40 mm vibratome coronal floating sections are ready for histology and for immunohistochemistry with anti-amyloid or other antibodies. Each vial contains 2 sections (#1).

Prestained sections (hematoxylin-eosin, #2 or anti-amyloid, #3) attached to silane-coated slides are also available. Other stains (microglia, cresyl violet, …) available on request.

References

Moechars et al. (1999) J. Biol. Chem. 274, 6483-6492

De Wachter et al. (2000) Exp. Gerontol. 35, 831-841




EuroPrice:  75,00 Euro ($82.50)

 

 

Section through transgenic Alzheimer mouse brain for histology and immunohistochemistry, hematoxylin-eosin stained

Section through transgenic Alzheimer mouse brain for histology and immunohistochemistry, hematoxylin-eosin stained
(Reference #GEN-3702)

slide with 2 brain sections, hematoxylin-eosin stained

Brains of transgenic Alzheimer mice, aged 1.5 - 3 years and bearing numerous amyloid plaques in subiculum, cortex and hippocampus were fixed in 4% paraformaldehyde. 40 mm vibratome coronal floating sections are ready for histology and for immunohistochemistry with anti-amyloid or other antibodies. Each vial contains 2 sections (#1).

Prestained sections (hematoxylin-eosin, #2 or anti-amyloid, #3) attached to silane-coated slides are also available. Other stains (microglia, cresyl violet, …) available on request.

References

Moechars et al. (1999) J. Biol. Chem. 274, 6483-6492

De Wachter et al. (2000) Exp. Gerontol. 35, 831-841




EuroPrice:  100,00 Euro ($110.00)

 

 

Section through transgenic Alzheimer mouse brain for histology and immunohistochemistry, anti-amyloid stained

Section through transgenic Alzheimer mouse brain for histology and immunohistochemistry, anti-amyloid stained
(Reference #GEN-3703)

slide with 2 brain sections, anti-amyloid stained

Brains of transgenic Alzheimer mice, aged 1.5 - 3 years and bearing numerous amyloid plaques in subiculum, cortex and hippocampus were fixed in 4% paraformaldehyde. 40 mm vibratome coronal floating sections are ready for histology and for immunohistochemistry with anti-amyloid or other antibodies. Each vial contains 2 sections (#1).

Prestained sections (hematoxylin-eosin, #2 or anti-amyloid, #3) attached to silane-coated slides are also available. Other stains (microglia, cresyl violet, …) available on request.

References

Moechars et al. (1999) J. Biol. Chem. 274, 6483-6492

De Wachter et al. (2000) Exp. Gerontol. 35, 831-841




EuroPrice:  175,00 Euro ($192.50)

 

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